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Institute History
UCI MIND was first established in 1995. At the time of its establishment, the center was named Institute for Brain Aging and Dementia (IBAD) and was led by the founding director, Dr. Carl W. Cotman. In January 2009, Dr. Cotman transitioned the directorship to Dr. Frank LaFerla, who had served as the Institute’s co-director during the previous 5 years. After the transition, a proposal was submitted in the Spring, 2009 and subsequently approved by Chancellor Michael Drake to change the name of the ORU to Institute for Memory Impairments and Neurological Disorders (UCI MIND). This name change more accurately reflects the breadth and depth of the evolving research program and clinical enterprise, and provides a more user-friendly name.
Since its inception, UCI MIND has grown into an internationally acclaimed site for excellence in Alzheimer’s disease and related dementias, and is particularly recognized for its research accomplishments in the following areas: amyloid biochemistry, animal models, calcium signaling, epidemiology, inflammation, mitochondrial dysfunction, protein aggregation, and successful aging. The Institute is also widely recognized for clinical research in Alzheimer’s disease and related dementias, Down syndrome, its program on the oldest old (The 90+ Study), and for conducting clinical trials.
The Institute is one of 29 Alzheimer’s disease centers (ADRC) supported by the National Institute for Aging, a branch of the National Institutes of Health. As an ADRC, one of our main functions is to educate the public we are able to integrate clinical and scientific research, as well as.
The Institute is one of 10 California Alzheimer Disease Clinical Centers (CADC) funded by the California Department of Public Health. The mission of the CADC is to diagnose and serve the needs of Orange County.



