Role of inflammation in degeneration and regeneration of injured CNS; human CNS stem cell engraftment
Neuroscience, Neural Circuits, Neural plasticity, Molecular Neuroscience, Behavior, Technique Development, Viral-genetic
adult synaptic plasticity, memory encoding, synaptic modulators, intellectual disability, autism, adhesion proteins, neurotrophic factors
Neuromuscular disorders, inclusion body myopathy, Paget disease, frontotemporal dementia, Prader Willi, morbid obesity, craniosynostosis
Alzheimer's disease, neurodegenerative diseases, myopathies, inflammation, microglia
Alzheimer’s disease; animal models, inclusion body myositis (IBM); Lewy body dementia; pre-clinical drug development; stem cell biology
Mechanisms of synaptic plasticity: LTP, glutamate receptors and cell adhesion molecules; Cellular deficits underlying cognitive impairment in animal model sof cognitive impairment; Cellular mechanisms of neuronal vulnerability in brain aging
survival analysis, analysis of high-dimensional brain image data, analysis of longitudinal data with change-points, terminal events, and variables subject to limit of detection.