Dr. Joshua Grill and colleagues at the University of Pittsburgh have been awarded a 3.5 million dollar grant by the National Institute on Aging to advance the field’s understanding of real-world patient and family member reactions to biomarker-informed Alzheimer’s disease and related disorders (ADRD) diagnoses and to provide critical information for directing post-diagnostic resources to monitor and support those most in need. Read the full news story about this important research here   Related posts: Precision health perspectives Leslie Thompson discusses how UCI’s collaborative approach can help usher in the next great advancement in healthcare July 11, 2022 In February,…

UCI MIND faculty member and psychiatrist, David Sultzer, MD, has been awarded a $12 million dollar grant by the NIA to test a novel prevention treatment. He, along with two other Southern California researchers will test an experimental vaccine to prevent Alzheimer’s disease.  The Orange County Register covered the story. Read the article here. Related posts: ‘First person’ interview with Gianna Fote in the Journal of Cell Science First author Gianna Fote was recently interviewed by the Journal of Cell Science for a newly-published paper. She provided commentary on her team’s new findings for UCI MIND: “In our recently published…

UCI MIND faculty member and Professor of Neurobiology and Behavior, Mathew Blurton-Jones Jones, PhD, has been awarded Early Career Innovator/Emerging Innovation of the Year by UCI Beall Applied Innovation. Read the full article here. Related posts: ‘First person’ interview with Gianna Fote in the Journal of Cell Science First author Gianna Fote was recently interviewed by the Journal of Cell Science for a newly-published paper. She provided commentary on her team’s new findings for UCI MIND: “In our recently published work we studied intracellular trafficking of Apolipoprotein E (APOE), a lipid-carrying protein. The APOE4 isoform of this protein… Hope Dies Last…

Irvine, Calif., Jan. 31, 2023 — Sustained support from philanthropists Joan and Don Beall to the the Institute for Memory Impairments and Neurological Disorders will allow for the continuation of an educational outreach program in Orange County high schools and the creation of a new research award for an early career researcher. “We are grateful for the Beall’s leadership, involvement and increased support of $100,000 a year for our educational and research programs,” said Joshua Grill, director of UCI MIND. “Support like theirs is critical to the institute’s mission and demonstrates the trust and commitment of the local community in…

UCI School of Medicine highlighted innovative research performed in the lab of Xiangmin Xu, PhD, UCI MIND faculty member and professor and Chancellor’s Fellow of anatomy and neurobiology in the UCI School of Medicine.  Dr. Xu and colleagues have found that sporadic Alzheimer’s disease can be modeled in a non-murine rodent called the Chilean degu. “Our findings, taken together, show spontaneous AD-like correlative phenotypes in cognitive performance and neuropathology in aged, outbred degus. This supports that aged degus are a useful and practical model of natural sporadic AD.” Xiangmin Xu Read the article in the February edition of the UCI School…

The recent FDA approval of lecanemab has generated a lot of buzz in recent days and UCI MIND director, Joshua Grill, PhD has been asked to comment in various highly visible media outlets including the Washington Post and today, in National Geographic.  Related posts: Cell therapy: a new frontier in Parkinson’s disease After decades of research into the causes and treatment of Parkinson’s disease, UCI Health neurologist Dr. Claire Henchcliffe is hopeful that a new cell therapy can finally bring meaningful relief to patients with the progressive neurodegenerative movement disorder. A national expert on Parkinson’s disease, she is one of a small group of…