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Neurobiology of Aging and Alzheimer’s Disease – T32

The University of California, Irvine’s Institute for Memory Impairments and Neurological Disorders (UCI MIND) training program has a solid track record over its 34-year history of producing highly successful scientists who enter academia or apply their training and knowledge in private industry to address dementia, a challenging and serious health problem for the nation and our growing senior population.

This multi-interdisciplinary training program, led by Drs. Craig Stark and Andrea Tenner, emphasizes preparation and instruction in the application of molecular and quantitative approaches to the elucidation of the cellular and molecular mechanisms of age-related neurodegeneration, brain plasticity during aging, and age-related changes in learning and memory. Faculty from the Schools of Biological Sciences, Medicine, Information and Computer Sciences, and from UCI MIND are part of the training program.

Leadership

Leader

Craig Stark, PhD

Department of Neurobiology & Behavior

Dr. Craig Stark is a professor in the department of Neurobiology and Behavior in the Charlie Dunlop School of Biological Sciences. He is also the Biomarker Core Leader for the UC Irvine ADRC.

Leader

Andrea Tenner, PhD

Department of Molecular Biology and Biochemistry

Dr. Andrea Tenner is a distinguished professor in the department of Molecular Biology and Biochemistry in the Charlie Dunlop School of Biological Sciences. She has has appointments in the department of Pathology in the School of Medicine and in Neurobiology and Behavior in the Charlie Dunlop School of Biological Sciences.

T-32 Trainees

Susana Furman

Mentor: Thomas Lane, PhD

Department: Neurobiology & Behavior

Destiny Berisha

Mentor: Bryce Mander, PhD

Department: Neurobiology & Behavior

Elizabeth (Ellie) Andrews

Mentor: Elizabeth Head, PhD

Department: Pathology and Laboratory Medicine

Thuy Lu

Mentor: Daniel Gillen, PhD

Department: Statistics

Daniela Cossio

Mentor: Liz Chrastil, PhD

Department: Neurobiology & Behavior

Jonathan Hasselmann

Mentor: Matthew Blurton-Jones, PhD

Department: Neurobiology & Behavior

Negin Barabadi

Mentor: Bryce Mander, PhD

Department: Cognitive Sciences

Jason Rothman

Mentor: Katrine Whiteson, PhD

Department: Molecular Biology and Biochemistry

Publications

  • Furman S, Green K, Lane TE. COVID-19 and the impact on Alzheimer’s disease pathology. J Neurochem. 2024 Oct;168(10):3415-3429. doi: 10.1111/jnc.15985. Epub 2023 Oct 18. PMID: 37850241; PMCID: PMC11024062.
  • Berisha DE, Rizvi B, Chappel-Farley MG, Tustison N, Taylor L, Dave A, Sattari NS, Chen IY, Lui KK, Janecek JC, Keator D, Neikrug AB, Benca RM, Yassa MA, Mander BA. Cerebrovascular pathology mediates associations between hypoxemia during rapid eye movement sleep and medial temporal lobe structure and function in older adults. bioRxiv [Preprint]. 2024 Jan 28:2024.01.28.577469. doi: 10.1101/2024.01.28.577469. PMID: 38328085; PMCID: PMC10849660.
  • Lu TV, Grill JD, Gillen DL; Alzheimer’s Disease Cooperative Study. Study Partner Type and Adverse Event Reporting in Mild-to-Moderate Alzheimer’s Disease Clinical Trials. J Alzheimers Dis. 2024;98(2):729-738. doi: 10.3233/JAD-231283. PMID: 38427487; PMCID: PMC10977362.
The loss of dopamine-producing neurons with Parkinson’s causes symptoms including a tremor, slow movements and muscle stiffness. Photograph: David Davies/PA

Interested in applying?

Faculty with eligible candidates, please send a letter of nomination, description of the trainees’ project and curriculum vitae to Janet Ko at jko@uci.edu.

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