As Orange County’s only state and federally funded Alzheimer’s Disease Research Center, UCI MIND is at the forefront of Alzheimer’s disease research. We have a variety of research participation opportunities for older adults with and without memory concerns. Click the tabs below to learn about our current research studies and clinical trials or contact our research team:
Phone: 949.824.0008
Email: research@mind.uci.edu
For more study details, contact us at research@mind.uci.edu or (949) 824-0008.
For more study details, contact us at research@mind.uci.edu or (949) 824-0008.
For more study details, contact us at research@mind.uci.edu or (949) 824-0008.
For more study details, contact us at hongrum1@uci.edu or (949) 824-8987.
The Longitudinal Study follows people with and without memory problems annually until the end of life. Through their lifetime commitment to research, our volunteers help us increase knowledge about memory and aging. For example, they help us understand:
Expert clinicians conduct a comprehensive annual evaluation that includes:
Feedback is provided in a family conference and/or a report, as most appropriate. Upon death, with the family’s permission, we perform a brain autopsy and provide final confirmation of the diagnosis.
Our investigators seek participants who meet the following criteria:
To determine eligibility, one of our research coordinators will interview you by phone and may ask you to complete some paperwork and/or come into the clinic for an in-person screening.
There is no charge to participate in any of our research studies.
As one of our longitudinal study participants, you will benefit from:
If you are interested in joining the Longitudinal Study or would like more information, contact 949.824.0008 or research@mind.uci.edu.
RESEARCH OPPORTUNITIES FOR ADULTS WITH DOWN SYNDROMEResearchers at the University of California, Irvine, under the direction of Dr. Ira T. Lott, are recruiting adults (age 18 and over, both female and male) with Down syndrome for the study, titled “Brain Aging and Dementia in Down Syndrome.” This study is funded by the National Institute on Aging. People with Down syndrome comprise a special populations of individuals at risk for Alzheimer’s disease type dementia. The purpose of this study is to improve our understanding of brain aging and dementia in Down syndrome.
Participation in this study will require yearly visits which consist of medical evaluation, neurologic evaluation, and assessments measuring your memory, thinking, and functional skills. The research visits will be conducted at the UC Irvine Institute for Clinic and Translational Science which has offices at both the UC Irvine campus in Irvine and the UC Irvine Medical Center in Orange. Participants can choose the research site of their preference. Each visit is expected to last approximately four to five hours. The evaluations in the study will be provided to participants at no cost.
There are no direct benefits of participation, however, the participant themselves, other individuals with Down syndrome, or the population as a whole may benefit from the conclusions drawn from the results of this study. Participants will not receive any compensation for their participation.
Researchers at the University of California, Irvine under the direction of Dr. Ira T. Lott, are seeking healthy adults with Down syndrome to participate in a research study about brain aging and Alzheimer’s disease. People with Down syndrome are at significantly increased risk to develop Alzheimer’s disease by age 40 years.
The study, entitled “Biomarker of Alzheimer’s Disease in Down Syndrome” will investigate biological factors that may be related to the development of Alzheimer’s disease in adults with Down syndrome. These biomarkers are likely to be important for the discovery of future therapies.
Approximately 100 adults with Down syndrome are sought to participate in the study. To be eligible, participants must have Down syndrome (with or without Alzheimer’s disease), and be age 40 or older. Study participants will be involved for a total of approximately 3 years of evaluations. During this time, participants along with their caregivers or family members will be asked to attend a total of 6-8 visits lasting 2-8 hours each over the study period.
The study includes:
Participants in this study may not revive any direct benefit to participation. Medical evaluations will be available to the participant’s physician. This study parallels research in Alzheimer’s disease within the general populations with a specific focus on Down syndrome.
The evaluations in this study are provided to participants at no cost.
Participants will be compensated up to $310.
If you know someone who may be interested in participating, or would like more information about these studies, please contact the study coordinator:
Eric Doran at 714.456.8443 or edoran@uci.edu
UC Irvine Medical Center, Department of Pediatrics
What is The 90+ Study?The 90+ Study is a research study to examine successful aging and dementia in those aged 90 years and beyond.
People 90 years or older who live in Southern California and are willing to undergo study procedures.
Clinical exams take place in the research office in Laguna Woods, CA or in your own home. Brain imaging is done in centers in Irvine and Newport Beach, CA. Transportation is provided if necessary.
There is no cost to you. The 90+ Study is funded by the National Institutes of Health.
With your participation in The 90+ Study, we hope to learn ways to improve quality of life for people as they grow older. Your participation may help others reach 90 years of age and beyond in better health.
Study Website: Click here
Phone: 949.768.3635
Email: study90@uci.edu
Address: 24361 El Toro Road Suite 150, Laguna Woods, CA 92867
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