An article in the New York Times is the latest to highlight the safety risks associated with recently approved new treatments for Alzheimer’s disease, lecanemab and donanemab. Being a carrier of the e4 genotype for the apolipoprotein (APOE) gene, is a known risk factor for the most serious side effects of these medications—swelling and bleeding in the brain collectively known as Amyloid Related Imaging Abnormalities (ARIA). The article highlights that in some of the earlier studies of these drugs, participants were not given the opportunity to learn their APOE genotypes. The field has historically been reluctant to disclose APOE results…
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RAMP trainees stand next to Dr. Lorna Carlin (middle). The Daily Breeze, a local Southern California online news source, highlighted the Research and Mentorship Program (RAMP), a collaborative training initiative between UCI MIND and the UCI School of Medicine to pair 2nd year medical students with faculty studying neurodegenerative diseases. The goal is to inspire future clinicians to pursue research and to specialize in neurology and geriatrics. The program is supported by Dr. Lorna Carlin and Hilarity for Charity, a non-profit organization started by Laura Miller-Rogen and Seth Rogen. Read the article here
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Dr. Vivek Swarup, associate professor of Neurobiology and Behavior and UCI MIND faculty member, was quoted this week in the popular online Alzheimer's disease publication, AlzForum, regarding 4 new AD risk genes that have been identified.
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We are excited to announce that in January 2025, Dr. Crystal M. Glover will join UCI MIND as the ADRC's Outreach, Recruitment, and Engagement Core Leader. She will also serve as Associate Professor of Neurology in the UC Irvine School of Medicine. Dr. Glover is a world-renowned applied social psychologist, mixed methodologist, and health disparities researcher focused on social determinants of health as it relates to aging and dementia. Along with her many international and national leadership roles, Dr. Glover is the inaugural Editor-in-Chief of Alzheimer's and Dementia: Behavior & Socioeconomics of Aging. She will continue the important work she started…
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Message from the Director Dear Friends of UCI MIND, This summer, we lost our founder, Dr. Carl Cotman. Under Dr. Cotman’s leadership, UCI became an independent ADRC in 2000. He recruited many of UCI’s most prominent researchers and leaders, such as David Cribbs, Claudia Kawas, and Frank LaFerla. He also lured UCI researchers into collaborative work on dementia, such as Andrea Tenner, Ira Lott, and Marcelo Wood. He launched the Southern California Alzheimer’s Disease Research Conference, now in its 35th year; secured the Neurobiology of Aging NIH training grant, now in its 41st year; and established the UCI ADRC brain…
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https://pennmemorycenter.org/breaking-the-tyranny-of-treatment-a-new-perspective-on-alzheimers-care/
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This Hispanic Heritage Month, we proudly recognize the invaluable contributions of our faculty, staff, community partners, and supporters who are dedicated to addressing Alzheimer’s disease and related dementias in the Hispanic and Latino communities. Our mission to advance Alzheimer’s research is strengthened by the passion and collaboration of those working on the front lines to ensure more inclusive research and care. At the forefront of these efforts is our Hispanic Community Advisory Board, led by Dr. Christian Salazar. The Board is instrumental in guiding us on best practices for building strong connections with the more than 1 million Hispanic and…
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AlzForum, the popular online publication for Alzheimer's researchers, published a summary of recent advances from the MODEL-AD teams and highlighted the work of the principal investigators at UCI, Drs. Kim Green, Andrea Tenner, and Frank LaFerla. The article also called attention to innovative research in the Green Lab, including work by postdoctoral scholar, Dr. Claire Butler and graduate student Kristine Tran. To read the article, click here.
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Dr. Leigh Turner, Professor of Health, Society and Behavior, School of Public Health As part of a collaborative project with USC and other faculty at UCI, Dr. Leigh Turner has been awarded a 2 million dollar grant from National Science Foundation to use biocomputing and stem cells to build neural networks to one day combat neurodegenerative diseases. Dr. Turner's role will be to study the ethical implications of this potential technology. Read the article in UCI News.
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https://news.uci.edu/2024/08/21/uc-irvine-discovery-of-item-memory-brain-cells-offers-new-alzheimers-treatment-target/
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