Tune in this Friday, September 6 @ 9AM for the next episode of our monthly Facebook LIVE series, "What have researchers learned from brain donations?" This month, we're joined by Edwin Monuki, MD, PhD. Dr. Monuki is a neuropathologist, meaning he specializes in the diagnosis of brain diseases by examining post-mortem tissue. His research aims to improve understanding of an understudied brain tissue known as the choroid plexus in an effort to develop potential new therapies for brain diseases, such as Alzheimer's. Dr. Monuki earned his medical and doctoral degrees from UC San Diego and currently serves as Professor and…
Read More
How are donated human brains used to study Alzheimer’s disease? October 25th Research Conference #SpeakerSpotlight: Dr. Julie Schneider is a board-certified Geriatric Neurologist and Neuropathologist, Professor of Pathology and Neurological Sciences at Rush University, and Associate Director of the Rush Alzheimer’s Disease Center. Dr. Schneider’s research focuses on linking pathology with risk factors and brain imaging to improve understanding of cognitive aging and dementia. Brain donation has been an invaluable resource for researchers to better understand the causes of and treatment options for Alzheimer's disease and related dementias. In the session, “Gifted Brains Yield Priceless Gains,” Dr. Schneider will discuss…
Read More
In this issue of MIND Matters: UCI MIND Scientists Discover Exercise Can Reprogram Genes Welcome, New Faculty & Staff New FDA Black Box Warning for Insomnia Medications Announcing the 10th Annual UCI MIND Gala Honorees... And more! Download Newsletter > Upcoming Events: Facebook LIVE Q&A Series: "What have researchers learned from brain donations?" Friday, September 6 | 9:00-9:30 am | UCI MIND Facebook Page Follow @UCIrvineMIND to receive notifications when we go LIVE Live online Q&A with Edwin Monuki, MD, PhD, Professor and Warren L. Bostick Chair of Pathology in the UCI School of Medicine. Attend the video live on our Facebook page or view archived…
Read More
How is Alzheimer’s disease diagnosed? October 25th Research Conference #SpeakerSpotlight: Dr. David Sultzer is a board-certified Geriatric Psychiatrist and Professor of Psychiatry & Human Behavior at UCI School of Medicine. After more than 20 years at UCLA and the West Los Angeles VA Hospital, Dr. Sultzer recently joined the team at UCI MIND and leads its clinical research operations, including clinical trials for new treatments. He is internationally recognized for his research activities to better understand the phenomenology, pathophysiology, and treatment of Alzheimer’s disease. In the session “Advances in Clinical Diagnosis," Dr. Sultzer will explain how doctors arrive at a…
Read More
How and why are mice used to study Alzheimer’s disease? October 25th Research Conference #SpeakerSpotlight: Dr. Frank LaFerla is a Chancellor’s Professor and the Dean of the UCI School of Biological Sciences. He served as Director of UCI MIND from 2009-2018 and continues to lead its NIH-designated Alzheimer’s Disease Research Center. Dean LaFerla invented the first mouse model to develop amyloid plaques and neurofibrillary tangles, leading to significant advances in our understanding of Alzheimer’s disease. In his presentation, Dean LaFerla will address how mouse models are used to study the disease, challenges with current models, and efforts toward new and…
Read More
Contributed by Bryce Mander, PhD Getty Images Our colleagues at UCSF recently published findings in the journal Alzheimer’s and Dementia examining how tau pathology in different brain diseases – Alzheimer’s disease, progressive supranuclear palsy, and corticobasal degeneration – impacts brain cells that are in charge of keeping us awake. This study reported several important findings: In all three diseases, there was a reduction in brain cells that help promote cortical arousal. In all three diseases, tau pathology was quite substantial in several of the wake-promoting cells in the brainstem region. Tau pathology in the brainstem in Alzheimer’s disease was associated with…
Read More
