UCI MIND Co-Directors, Drs. Joshua Grill and Frank LaFerla with Maria Shriver at the annual UCI MIND gala on December 2, 2017 at the Balboa Bay Resort More than 5.5 million Americans have Alzheimer’s disease. Two-thirds of them are women. The initiative will fund critical new women-based research. ORANGE COUNTY, Calif., (December 5, 2017) — A new partnership in Orange County, California is seeking answers to an essential question affecting global health: Why do more women get Alzheimer’s disease than men? UCI MIND, the University of California at Irvine’s Institute for Memory Impairments and Neurological Disorders, has announced a new research initiative…
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The National Institute on Aging has announced funding of a new clinical trial network, charged with testing the most promising potential treatments and preventions for Alzheimer’s disease over the coming years. The $70 million grant includes UCI MIND as a clinical trial site and Dr. Joshua Grill as a unit leader. Press release >
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In a study published today in Alzheimer’s & Dementia, UCI MIND faculty members Drs. Claudia Kawas and Maria Corrada, and colleagues at UCLA, reported the first estimates of preclinical Alzheimer’s disease (AD) and mild cognitive impairment (MCI) prevalence in the United States. According to the study, 2.4 million Americans are living with MCI due to AD (memory and other cognitive problems that do not meet criteria for dementia), and this number is expected to more than double by 2060. Moreover, the researchers estimated about 47 million Americans have preclinical AD, the presence of amyloid accumulation and/or neurodegeneration with no symptoms of memory…
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by Joshua Grill, PhD Numerous studies have shown links between lifestyle factors and risk for Alzheimer’s disease and other dementias. A new assessment of available studies by investigators at University College in London examines one lifestyle factor, marriage, and finds that people with a spouse may be at decreased risk for Alzheimer’s disease and other dementias. In contrast, widows and people who have been single their whole lives may be at 20-40% increased risk. At UCI MIND, a variety of studies have explored the implications of spousal status on Alzheimer's disease clinical trials. In particular, we've shown that people with…
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Don’t miss an unforgettable evening of fun and philanthropy in support of Alzheimer’s disease research this Saturday, December 2nd at the Balboa Bay Resort in Newport Beach! If you haven’t done so already, purchase your ticket or table today to join esteemed researchers from UCI MIND, gala honorees Maria Shriver and Suzy Melin, and philanthropists for one night that will have a lasting impact in the fight against Alzheimer’s disease. A December to Remember Sponsors The Beaumont Family, in Honor of Dr. Jacqueline DuPont The Covington Elite OC Productions HCP, Inc. Susan and Frank Kavanaugh Robert and Barbara Kleist The…
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In this issue of MIND Matters: New grants awarded for cutting-edge science Interview with research participant, Jerry Leth Philanthropist highlight, Steve O'Leary Maria Shriver, celebrity honoree for 8th annual A December to Remember gala Donations to UCI MIND, September 2016 to September 2017 Read more here >
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Saturday, December 2nd, is your opportunity to directly support cutting-edge research at UCI MIND, OC’s only state and federally designated Alzheimer’s Disease Research Center! Join hundreds of community members for an evening of fun and philanthropy at A December to Remember gala at the Balboa Bay Resort. Mingle with esteemed researchers from UCI and internationally renowned Alzheimer’s advocate, Maria Shriver, who will be honored at the event for her work with The Women’s Alzheimer’s Movement.A December to Remember Sponsors The Beaumont Family, in Honor of Dr. Jacqueline DuPont The Covington Susan and Frank Kavanaugh Robert and Barbara Kleist The Melin…
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Microsoft co-founder and philanthropist, Bill Gates, blogs on why he has decided to invest in Alzheimer's disease research. He notes, "What I’ve heard from researchers, academics, funders, and industry experts makes me hopeful that we can substantially alter the course of Alzheimer’s if we make progress in five areas: We need to better understand how Alzheimer’s unfolds. We need to detect and diagnose Alzheimer’s earlier. We need more approaches to stopping the disease. We need to make it easier to get people enrolled in clinical trials. We need to use data better." Read more about Gates' commitment to Alzheimer's disease…
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A new study published in JAMA Neurology explored participants' perspectives on receiving amyloid PET scan results as part of an Alzheimer’s disease prevention clinical trial, the A4 study. Participants at UCI MIND contributed to this important research, led by investigators at the University of Pennsylvania (read more about the study here). Amyloid PET is a biomarker test that could someday be used to identify people at increased risk for Alzheimer's disease who may benefit from preventative or disease-delaying treatments. Biomarker testing such as amyloid PET is being used more and more in the research setting to identify participants appropriate for Alzheimer's disease…
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(from left) Andrea Wasserman, Frank LaFerla, David Baglietto-Vargas, Grant MacGregor, Ali Mortazavi, Kim Green, Andrea Tenner UCI MIND co-director Frank LaFerla and Drs. Andrea Tenner, Kim Green, Grant MacGregor, Marcelo Wood, and David Baglietto-Vargas were awarded an $11.35 million grant from the National Institutes of Health to create the next generation of mouse models to study Alzheimer’s disease. The news released by UCI on October 9 continues to draw local media attention, featured in the LA Times/Daily Pilot and Newport Beach Patch this morning. UCI MIND is already home to the discovery of the first ever mouse model to develop…
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