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UCI MIND Faculty leads study to model sporadic Alzheimer’s disease in degus

By January 30, 2023Carousel Slider, In the News

UCI School of Medicine highlighted innovative research performed in the lab of Xiangmin Xu, PhD, UCI MIND faculty member and professor and Chancellor’s Fellow of anatomy and neurobiology in the UCI School of Medicine.  Dr. Xu and colleagues have found that sporadic Alzheimer’s disease can be modeled in a non-murine rodent called the Chilean degu.

“Our findings, taken together, show spontaneous AD-like correlative phenotypes in cognitive performance and neuropathology in aged, outbred degus. This supports that aged degus are a useful and practical model of natural sporadic AD.” Xiangmin Xu

Read the article in the February edition of the UCI School of Medicine News and Events

The Chilean Degu