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Alzheimer’s biomarkers in Down syndrome parallel late-onset disease

Dr. Elizabeth Head (left) studies Down syndrome and Alzheimer’s disease at UCI.


In an accompanying editorial, [UCI MIND Professor] Elizabeth Head, PhD, of University of California Irvine, and Beau Ances, MD, PhD, of Washington University St Louis, wrote,

“Fortea and colleagues noted similarities between biomarkers reflecting Alzheimer disease pathogenesis in individuals with Down syndrome and individuals with late onset and autosomal dominant Alzheimer disease. These results provide strong evidence that studies of people with Down syndrome can inform research on late-onset and autosomal dominant Alzheimer disease.”

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