Contributed by Joshua Grill, PhD Yesterday morning, Biogen announced the company’s intention to file with the FDA for approval of Aducanumab, a monoclonal antibody that until recently had been in development as a potential disease-modifying therapy for Alzheimer’s disease. The news came as a shock to us, since two large Phase 3 clinical trials of Aducanumab had been halted for futility earlier in 2019. “Futility” is defined as an early indication that a trial is not likely to demonstrate a drug benefit. As a site for one of those trials, we – along with the research participants and the entire…
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Facebook Live Series - ASK THE DOC: Alzheimer's Research Today! This monthly series features short talks and Q&A with experts from the University of California, Irvine Institute for Memory Impairments and Neurological Disorders (UCI MIND), 1 of 32 congressionally designated Alzheimer’s Disease Research Centers in the nation. Join UCI MIND on Facebook (@UCIrvineMIND) the first Friday of every month from 9:00-9:30 AM PST to learn about advances in research to improve Alzheimer’s disease diagnosis, treatment, and prevention. Episode 9: "When should I see a doctor about memory concerns?" This month, we're joined by UCI MIND Senior Neuropsychologist, Malcolm Dick, PhD.…
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Join us for the 30th annual research conference on October 25th at the Irvine Marriott Hotel. Come learn from internationally renowned experts about how far we have come and where we are headed in the battle against Alzheimer's disease. Register now at http://conference.mind.uci.edu
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Tune in this Friday, October 4 @ 9AM for the next episode of our monthly Facebook LIVE series, "When should I see a doctor about memory concerns?" This month, we're joined by Malcolm Dick, PhD. Dr. Dick has served as an Alzheimer's disease researcher and clinician at UCI since earning his doctorate from University of South Carolina in 1984. He is a highly respected neuropsychologist among his colleagues and the patients and families he serves. Throughout his tenure, Dr. Dick has participated on 24 clinical trials, mentored 54 trainees, presented hundreds of lectures, and published numerous articles and book chapters. Dr. Dick has dedicated his life's work…
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Contributed by Joshua Grill, PhD Dorene Rentz and her husband, Ray Berggren, at their home in Natick, Mass. Dr. Rentz helped design the cognitive tests used in the A4 Alzheimer’s clinical trial in which her husband is now participating. Photo credit: M. Scott Brauer for the Wall Street Journal Alzheimer’s disease is a public health crisis. UCI MIND investigators regularly speak in public to increase awareness of the magnitude of the problem and the urgency of our work (see Event Calendar). But many of us leave the clinic, laboratory, or office to face this crisis at home as well. In this excellent…
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