Dr. Joshua Grill, a University of California, Irvine, Alzheimer’s researcher, who collaborated with Eisai and other researchers to analyze two trials for Leqembi and two for an earlier anti-amyloid drug, also found that Black, Hispanic and Asian people were more likely to be screened out of clinical trials because the amount of amyloid in their brain was below the trial’s threshold. The researchers intend to submit the findings for publication.
“Is it that it’s not Alzheimer’s disease? Is something else causing their cognitive problems across all these studies? Is it that the biomarkers don’t quite work the same in those communities, or is it something else that we’re not able to measure?” Grill said.
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