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Insight: Promising new Alzheimer’s drugs may benefit whites more than Blacks

Insight: Promising new Alzheimer's drugs may benefit whites more than Blacks

Barrington and Vickie Riley pose at the Emory University Brain Health Center in Atlanta, Georgia, U.S., July 12, 2023. The Riley’s, who have been married more than 35 years, participated in the Charlie and Harriet Shaffer Cognitive Empowerment Program. Barrington Riley has mild cognitive impairment. REUTERS/Alyssa Pointer

Dr. Joshua Grill, a University of California, Irvine, Alzheimer’s researcher, who collaborated with Eisai and other researchers to analyze two trials for Leqembi and two for an earlier anti-amyloid drug, also found that Black, Hispanic and Asian people were more likely to be screened out of clinical trials because the amount of amyloid in their brain was below the trial’s threshold. The researchers intend to submit the findings for publication.

“Is it that it’s not Alzheimer’s disease? Is something else causing their cognitive problems across all these studies? Is it that the biomarkers don’t quite work the same in those communities, or is it something else that we’re not able to measure?” Grill said.

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