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(VIDEO) UCI MIND researchers use human stem cell models to understand immunity in Alzheimer’s disease

Amanda McQuade, graduate student in Mathew Blurton-Jones’ lab at UCI MIND, discusses findings from their new study using induced pluripotent stem cells (iPSC), donated from participants at the UCI Alzheimer’s Disease Research Center, and CRISPR gene editing to improve understanding of the role of immunity in Alzheimer’s disease. Click below to view the video, and access the publication at this link:



Amanda McQuade, MS

Amanda McQuade is a graduate student in the department of Neurobiology and Behavior working with Dr. Mathew Blurton-Jones. Her graduate work focuses on using CRISPR to study risk mutations for Alzheimer’s disease in human cell models and chimeric animal models. Her ongoing studies highlight the critical need for more research into immune function in neurodegenerative disease. McQuade is currently acting as a Co-Chair of the trainee program on Research and education within UCI MIND, ReMIND, which focuses on community outreach and trainee education.